| Nevus of Ota | |
|---|---|
| Classification and external resources | |
| ICD-10 | D22.3 (ILDS D22.301) |
| DiseasesDB | 32588 |
| eMedicine | DERM/290 |
| MeSH | D009507 |
Nevus of Ota (also known as "congenital melanosis bulbi,"[1] "nevus fuscoceruleus ophthalmomaxillaris," "oculodermal melanocytosis",[2]:700 and "Oculomucodermal melanocytosis"[1]) is a blue hyperpigmentation[3] that occurs on the face. It was first reported by Dr. M. T. Ota of Japan in 1939.[4]
Nevus of Ota is caused by the entrapment of melanocytes in the upper third of the dermis. It is found on the face unilaterally and involves the first two branches of the trigeminal nerve. The sclera is involved in two-thirds of cases (causing an increased risk of glaucoma). It should not be confused with Mongolian spot, which is a birthmark caused by entrapment of melanocytes in the dermis but is located in the lumbosacral region. Women are nearly five times more likely to be affected than men, and it is rare among white people. Nevus of Ota may not be congenital, and may appear during puberty.
Q-switched laser has been used for treatment.[5][6]
Hydroquinone preparations are also helpful in partially treating this defect.
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